- 3-pages academic summary;
[employment]
[education]
[writings]
[lectures]
[awards]
[training]
[grants]
[science management]
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- Since 2023: Senior scientist
- CNRS, European Genomic Institute for Diabetes; Lille, FR. Principal investigators : Amélie BONNEFOND, Philippe FROGUEL.
- 2019-2023: Consultant in data analysis, modelling, science copywriting, and language translation
- aSciStance Limited (founder and director); Cambridge, UK.
- 2012-2018: Senior Group leader
- Babraham Institute; Babraham, Cambridge, UK.
- 2014-2015: Chief Data Officer
- Curie Institute; Paris, FR.
- 2003-2012: Group leader
- EMBL-EBI; Hinxton, Cambridge, UK.
- 2001-2003: Researcher
- CNRS URA 2182, Récepteurs et Cognition; Institut Pasteur, Paris, FR. Principal investigator : Jean-Pierre CHANGEUX.
- 1999-2001: Post-doctoral fellow
- Computational Cell Biology,\; University of Cambridge, Cambridge, UK. Principal investigator : Dennis BRAY.
- 1992-1999: Undergraduate, PhD student, and post-doctoral fellow
- CNRS URA D1284, Neurobiologie Moléculaire; Institut Pasteur, Paris, FR. Principal investigator : Jean-Pierre CHANGEUX.
- 1991: Undergraduate student
- INSERM 153, Service of Développement, Pathologie, Régénération du système neuromusculaire; Institut du fer à moulin, Paris, FR. Principal investigator: Michel FARDEAU.
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Writings
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Full list of Scientific research publications, with PDF versions and links to the publisher site and public repositories.
Literary publications (own and book translations).
Lectures
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See the dedicated lecture page.
Teaching and student supervision
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PhD supervisions
Manusnan Suriyalaksh (2016-2018), Juliette Pearce (2016-2018), Janna Hastings (2015-2018), Vincent Knight-Schrivjer (2014-2018), Benedetta Frida Baldi (2009-2015), Christine Seeliger (2009-2014), Michele Mattioni (2008-2012), Lu Li (2007-2010), Melanie I Stefan (2006-2009), Dominic P Tolle (2005-2009), Zhi-Yan Han (1999-2002)
PhD visitors
Lucas Marmiesse (2015), Anna Zhukova (2016), Youwei Zheng (2011), Nathan Skene (2010), Ron Henkel (2009), Koray Dağan Kaya (2008), Christian Knüpfer (2007), Dagmar Köhn (Waltemath) (2007)
Undergraduate interns
Adrien Leroy (2018), Stephen Cole (2017), Agathe Delaune (2017), Derya Sebukhan (2017), Letizia Vestito (2017), Katrīna Daila Neiburga (2016), Krutic Patel (2016), Hoa Le (2014), Ioana Olan (2014), Simon Delagneau (2014), John Gowers (2013), Grigalius Taukanska (2013), Marija Jankovic (2013), Yangyang Zhao (2012), Ishan Ajmera (2011), Denis Brun (2011), Michael Schubert (2011), Anna Zhukova (2011), Gael Jalowicki (2011), Jean-Baptiste Pettit (2010), Karim Tazibt (2010), Marine Dumousseau (2009), /a> (2008), Ranjita Dutta-Roy (2008), Kedar Nath Natarajan (2008), David Marshall (2007), Antonia Mayer (2007), Anika Oellrich (2007), Enuo He (2006), Arnaud Henry (2006), Camille Laibe (2006), Renaud Schiappa (2006), Lu Li (2005), Alexander Broicher (2004), Marie-Ange Djite (2004).
PhD juries
Lucas Marmiesse (2016), Sylvain Soliman Habilitation (2015), Samuel Croset (2014), Lukas Endler (2012), Allyson Lister (2011), Andrew Miller (2011), Dagmar Köhn (Waltemath) (2011), Aurelien Rizk (2011), Carito Guziolowski (2010), Sarala Wimalaratne (2009), Benjamin Hall (2007), Pim Van Nierop (2007), Stéphanie Weiss (2006), Anne-Sophie Villegier (2005), Geoffroy Golfier (2004)
Courses
Organiser (and lecturer)
EBI course In silico systems biology (April 2010, April 2011, April 2012, June 2013, June 2015, July 2016, July 2017, June 2018 ); WT/E-MeP Advanced Training Workshop in Bioinformatics of Membrane Proteins, Hinxton, UK (February 2008); Okinawa Computational Neuroscience Course 2006, OIST, JP (Jul 2006);
Lecturer
Advances in Systems and Synthetic Biology, Strasbourg (2015), Cambridge University Technical College (2015), Part III Systems Biology, University of Cambridge, UK (2013, 2014); EBI course "The Systems Biology Modelling Cycle", Hinxton, UK (2014); Instituto Gulbenkian de Ciência PhD student course, Lisbon, PT (2012); SystemsX.ch/SIB Summer School, Kandersteg, CH (2011); Summer school of the Center for Genomic Regulation, Barcelona, SP (2011); EBI-Wellcome Trust Summer School in Bioinformatics (Jun 2010, Jun 2011, Jun 2012); International Genetically Engineered Machine competition (iGEM) - Cambridge (2007, 2009); EBI training on Networks and Pathways (Jun 2009); APO-SYS data management workshop, Hinxton, UK (June 2008); SysBioMed Winter School, Tenerife, ES (Feb 2007); EMBL international PhD program, Heidelberg, DE. (Oct 2007, Oct 2005); Symbionic course on Methods, data handling and standards in neuronal systems biology, Trieste, IT (Aug 2005)FEBS course 1st Advanced Course on Systems Biology: From Molecules & Modeling To Cells, Gosau, AT (Mar 2005); ESF course Modelling Metabolic and Signal Transduction Networks, Oxford, UK (Sep 2005); Diploma of Advanced Studies of Neurobiology and Pharmacology (École Normale Supérieure), Paris, FR (Nov 2002).
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Grants
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BBSRC |
Molecular and Cellular Mechanisms of Host Defence and Immunosenescence: a BBSRC Strategic Programme
01/04/2017-31/03/2022. |
BBSRC |
Epigenetics and cellular heterogeneity in development and ageing
01/04/2017-31/03/2022. |
BBSRC |
Molecular mechanisms underpinning healthy ageing, a BBSRC Strategic Programme
01/04/2017-31/03/2022. |
NIH |
Continued support and development of SBML (co-I)
01/05/2016-30/04/2019. |
BBSRC |
MultiMod, flexible management for multi-scale multi-approach models in biology
01/06/2016-31/05/2019. |
BBSRC |
UK Multi-Scale Biology Network
06/2015-05/2018. |
MRC |
Modification of the host lipidome by Rhinovirus infection (Co-I)
03/07/2014- |
BBSRC CASE |
Systems Pharmacology Models of Druggable Pharmaceutical Targets and Disease Mechanisms
31/03/2014-30/03/2018. |
EU commission |
Systems biology of pathways involving brain ageing (AgedBrainSYSBIO) (co-I)
01/01/2013- |
BBSRC ISP |
A systems approach to understanding lipid, Ca2+ and MAPK signalling networks (Co-I)
01/04/2012-31/07/2017. |
BBSRC |
Linking data with Identifiers.org
01/08/2012 |
EU commission |
Infrastructure for Systems Biology Europe (ISBE) (Co-I)
27/09/2012 |
BBSRC BBR |
BioModels Database, the comprehensive resource for computational models in Biology
01/08/2012-30/07/2015 |
IMI-JU |
Open PHACTS (Co-I)
01/02/2012 |
BBSRC |
How do cells shape and interpret PIP3 signals (Co-I)
01/05/2011-30/04/2016. |
IMI-JU |
Drug Discovery Model Repository (DDMoRe) (Co-I)
01/03/2011-28/02/2016. |
BBSRC |
First COMBINE meeting: Bridging model structure, semantics and representation.
06/10/2010-09/10/2010. |
NIH |
Continued support and development of SBML (co-I)
01/09/2010-31/12/2012. |
EU commission |
Synaptic Systems: dissecting brain function in health and disease (SynSys) (Co-I)
01/07/2010-30/06/2014.
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EU Commission |
ELIXIR technical feasibility study 13.3 (Co-I)
01/03/2008-31/08/2009 |
BBSHDRRC BBR |
BioModels Database: a unified resource for Systems Biology models. 01/01/2008-31/12/2011 |
NIH |
Continued support and development of SBML (Co-I)
01/09/2007-31/08/2010. |
BBSRC |
Interfacing standards and ontologies in Systems Biology. 01/04/2007-31/03/2011 |
BBSRC |
Software infrastructure to support the standard of model curation and annotation MIRIAM. 01/09/2006-31/08/2007 |
NEDO |
Development of The Systems Biology Graphical Notation, a standard graphical notation for diagrams of computational models in biology (Co-I)
01/11/2005-30/06/2008 |
NIH |
Continued support and development of SBML (Co-I)
01/09/2005-31/01/2007 |
EU commission |
The European Membrane Protein Consortium (e-MeP) (Co-I)
01/07/2004-31/03/2009.
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ESF |
The Meso-telencephalic Dopamine Consortium (DopaNet). 01/01/2003-31/12/2005.
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Evaluation and management of science
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- Member of the editorial board of:
- BMC Systems Biology (2006-2018, associate editor 2008-2018), PeerJ (2012-2014), NPJ Systems Biology and applications (associate editor 2014-2018)
- Meeting organisation:
- SBML hackathon 2004, hackathon 2009, SBGN 1, SBGN 2, SBGN 2.5, SBGN 3, SBGN 3.5, SBGN 4, COMBINE 2010, COMBINE 2011, COMBINE 2012, COMBINE 2013, HARMONY 2011, HARMONY 2012, EMBO meeting 2015 special interest symposium on epigenetics and cell fate.
- Member of conference scientific committee for
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BioNetVisa 2014,
BioNetVisa 2015,
BioNetVisa 2016,
BioNetVisa 2017,
BioSysBio 2009, BioSysBio2008,
CBIBM 2014,
CIBB 2009,
CMSB 2008, CMSB 2005,
ICBO 2013, ICBO 2012,
ICSB 2016,
ICSB 2014,
ICSB 2010,
ICSB 2008,
ICSB 2006,
ECCB 2008,
ISMB/ECCB 2015, chair of the theme "systems", ISMB/ECCB 2017,
FMMB 2014,
- Standardisation editorial boards:
- co-chair of the IUPHAR sub-committee on the nomenclature of nicotinic acetylcholine receptors, Systems Biology Markup Language - SBML (2006-2008, 2011-2013, 2016-2018), Systems Biology Graphical Notation (2008-2012), Simulation Experiment Description Markup Language (2008-2013)
- Grant panels:
- Swiss National Fund (2016-2018), ERC Advanced Grants (2015-2018), MRC Biomedical Informatics Fellowship (2014), FRM Bioinformatics (2013, 2014), Forschungszentrum Juelich GmbH (2013), agreenskills (2013), BMBF eBio (2011), BBSRC TRDF (2010) and STRDF (2011), ANR SYSCOMM (2008, 2009), ANR/BBSRC Systems Biology (2007)
- Steering committee:
- The European Membrane Protein Consortium - E-MeP (2004-2007), AgedBrainSYSBIO (2013-), UK Multi-Scale Biology community network (2015-)
- Scientific advisory committees:
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- AERES, EU IP ENFIN, BioPAX, BBSRC Plant Models Portal (2008-2010), Research Centre of the Institut Curie (2009-2018), German Virtual Liver Network (2010-2014), COPASI BBR (2013-), Heidelberg Centre for Organismal Studies (2013), Montpellier Pôle Biosanté Rabelais (2013), labex EpiGenMed (2013-), Toulouse Centre of Integrative Biology (2016-), Cochin Institute (2016-), UK Quantitative Systems Pharmacology Network
- Expert groups:
- INSERM "Tobacco: Understand the addiction to act" (2003), EU "Systems Biology for Medical Applications" (2007), BBSRC "Digital Organisms" (2012), Science Europe "Multidisciplinary career paths"
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